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Of these 40 patients, they were randomly assigned to receive Gabapentin (1200 mg) or a placebo.

The administration of either Gabapentin or the placebo occurred approximately 2 hours before surgery.

In fact, some sources hypothesize that nearly 90% of Gabapentin prescriptions are off-label.

It is difficult to draw generalized conclusions from the results of this study, but the outcome indicates that Gabapentin may be effective among individuals with panic disorder.

Though the drug hasn’t been tested specifically for the treatment of panic disorder, additional research may be warranted.: Many people experience significant anxiety during public speaking.

There is mounting evidence that Gabapentin may be an effective intervention for various types of anxiety including: generalized anxiety disorder, social anxiety disorder, and panic disorder.

There is considerable research documenting the efficacy and safety of Gabapentin for anxiety disorders.

A randomized, placebo-controlled, double-blind study was conducted to determine the safety and efficacy of Gabapentin among individuals diagnosed with social anxiety disorder.

A total of 69 participants were divided into two groups: one received Gabapentin (900 mg to 3600 mg daily) and the other received a placebo. Researchers noted that social anxiety levels plummeted among those taking the Gabapentin compared to the placebo.Research and interest in Gabapentin began in the 1990s for anxiety disorders due to its unique GABAergic mechanism of action.Nearly every published study has found Gabapentin to be superior in efficacy for the reduction of anxiety when compared to a placebo.: Gabapentin has been researched since the 1990s for its effect as an anxiolytic agent.Authors of the study suggest that based on the limited data, Gabapentin has a favorable risk-benefit ratio for the treatment of social anxiety disorder.Even in the 1990s, there was notable evidence to suggest that Gabapentin may be a favorable intervention for anxiety – particularly social subtypes.: In one study analyzing the efficacy of Gabapentin as an adjunct treatment for bipolar disorder, it was discovered that improvements were most notable on anxiety-somatization measures of the Hamilton Rating Scale for Depression (HAM-D).Researchers used a simulated public speaking (SPS) task to evaluate both level of anxiety and mood of the participants.